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镰刀菌酸对大白鼠血压的影响
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摘要:
镰刀菌酸(5-丁基吡啶-2-羧酸)是由镰刀菌所产生的一种弱酸性次生代谢产物,对植物有致萎蔫作用,近年来发现它对动物具有降低血压的作用.本实验的目的是证明镰刀菌酸对大白鼠血压的影响。实验结果表明:1.镰刀菌酸确有降低大白鼠血压的作用。2.使大白鼠血压显著下降的镰刀菌酸浓度为15mg/kg 体重。3.注射后2小时己明显下降,至5-8小时继续下降或维持,23小时后大白鼠的血压都恢复至注射前的水平。
关键词:  大白鼠  腹腔注射  降压作用  注射量  降低血压  镰刀菌酸  次生代谢产物  
DOI:
基金项目:
THE EFFET OF FUSARIC ACID ON THE BLOOD PRESSURE OF THE RAT
Abstract:
Fusaric acid is produced by Fusarium spp.It is a weak acid of meta- bolite.Fusaric acid can wither up plants.In recent years it has disco- vered that fusaric acid has hypotensive effect on animals. The purpose of our experiment is to certified that fusaric acid acts on blood pressure of the rat. The experimental result demonstrates:1.Fusaric acid has hypotensive effect on rat.2.The minimum concentration of fusaric acid which has hypotensive effect is 15mg/kg.3.After injection 2 hours blood pressu- re decrea...
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